In 2023 Nikku Madhusudhan and four other scientists created quite a stir. They authored a paper entitled "Carbon-bearing Molecules in a Possible Hycean Atmosphere." Researching a planet called K2-18 b revolving around another star, the paper claimed to have found "potential signs of dimethyl sulfide (DMS), which has been predicted to be an observable biomarker in Hycean worlds." The term "Hycean worlds" refers to planets in other solar systems that may be entirely covered by an ocean. The term "biomarker" refers to something that may be a sign of life. A very simple compound, dimethyl sulfide is not any type of building block of life. But on Earth dimethyl sulfide is sometimes produced by life.
But there were some reasons why the attempt to insinuate a biomarker was very dubious. One reason was that the claims about "potential signs of dimethyl sulfide" was a kind of "reading tea leaves" affair, in which scientists were analyzing the faintest of faint signals, rather like someone squinting at something on the horizon miles away. That type of observation offers plenty of opportunity to see what you want to see, by interpreting marginal hard-to-interpret just-barely-detectable data in some way that fits your cherished desires, rather than a hundred other ways.
Then there is the fact that when scientists do observations like this, they are picking up signals from many different chemical sources, with the signals being all mixed up. It's a recipe for false alarms, rather like someone in a very crowded high school cafeteria trying to listen to what someone at a different cafeteria table far away is saying.
Then there is the fact that the paper failed to detect any water at this planet. The paper stated this:
"We do not find significant contributions due to H2O or NH3, but find 95% upper limits of -3.21 for log(XH2O) and -4.46 for log(XNH3 ) in the no-offset case. These upper limits are also consistent with those from the other retrieval cases, as shown in Table 2. The non-detections of both molecules are important considering their strong spectral features and detectability expected in the 0.9- 5.2 µm range (Madhusudhan et al. 2021; Constantinou & Madhusudhan 2022). The non-detection of H2O is at odds with its previous inference using the HST WFC3 spectrum in the 1.1-1.7 µm range (Tsiaras et al. 2019; Benneke et al. 2019a; Madhusudhan et al. 2020)."
It is generally agreed that water is absolutely necessary for any form of life of life to exist. The apparent non-presence of water at K2-18 b is a reason for thinking that life does not exist there.
Despite the paper's failure to detect water, and its weak mention of a mere mention of "potential signs of dimethyl sulfide," the world's "give us an inch and we'll take a mile" science news press began publishing a flood of misleading stories falsely claiming that some promising sign of life had been found. An example was this story on www.yahoo.com, which very badly misinformed us by stating this:
"The ability of a planet to support life depends on its temperature, the presence of carbon and probably liquid water. Observations from JWST seem to suggest that that K2-18b ticks all those boxes."
No, the scientific paper said that water was not detected on K2-18b, even though a sensitive test was made that should have detected traces as low as 1 part in a billion.
After the "sugar rush" of this flood of misleading stories, other scientists got busy examining the data on the distant planet K2-18 b, to see whether there was any decent evidence for dimethyl sulfide. In 2024 scientists produced a paper arguing that K2-18 b was not a "Hycaean" planet covered by an ocean, but instead a gas planet like Neptune with no ocean. The paper was "JWST Observations of K2-18b Can Be Explained by a Gas-rich Mini-Neptune with No Habitable Surface" authored by Nicholas F. Wogan and others.
Then in early 2025 there was published the paper "A Comprehensive Reanalysis of K2-18 b's JWST NIRISS+NIRSpec Transmission Spectrum." It reanalyzed the data on K2-18 b and says "we find no statistically significant or reliable evidence for CO2 or DMS [dimethyl sulfide]." The paper had 16 authors, as compared to only five authors of Madhusudhan's paper. The 16 authors had found that Madhusudhan's claims about dimethyl sulfide at K2-18 b were unfounded.
But now Madhusudhan is back with a new paper, trying to persuade us that dimethyl sulfide exists on K2-18 b. It is a paper entitled "New Constraints on DMS and DMDS in the Atmosphere of K2-18 b from JWST MIRI." He has some new observations, but only a scanty affair. It's a mere six hours of observations done with the James Webb Space Telescope, on April 26, 2025. Madhusudhan and his small team has put this data through some very arbitrary and gigantically convoluted analysis pipeline, one that was probably selected to maximize the chance of being able to claim that dimethyl sulfide exists on K2-18 b. The raw data gathered is shown below (Figure 1 from the paper). Ignore the red line, which is not part of the raw data.

Data like this does nothing to naturally suggest the existence of dimethyl sulfide. The James Webb Space Telescope has nothing like a "dimethyl sulfide detector" comparable to a carbon monoxide detector in a home. But it is possible for a scientist eagerly hoping to claim some evidence of dimethyl sulfide to arbitrarily analyze such data, to try and gin up something that can be claimed as evidence of dimethyl sulfide. At least seven long paragraphs of the paper discuss the incredibly elaborate rigmarole that is going on in Madhusudhan's analysis pathway. It would be way, way too charitable to describe this analysis pathway as a Rube Goldberg machine. It would be more accurate to say that the analysis pathway is some incredibly weird analytic contraption that makes the crazy-looking machines of Rube Goldberg look simple and straightforward in comparison. Below is a paragraph giving us only one eighth of the "keep torturing the data until it confesses" craziness that was going on:
"We use the 1-D spectra time series to construct a white
light curve (between 4.8-10 µm). We exclude the first
250 integrations, where the systematic trend is most extreme. We identify outliers on the white light curve, ±
2.5-σ from a rolling median, and replace the 1-D spectra corresponding to these outliers with linearly interpolated spectra from adjacent integrations. We scale
the error bars on the light curve points such that the
average error bar equals the observed standard deviation of the scatter in the out-of-transit residuals. We
use emcee (Foreman-Mackey et al. 2013) to perform
a Markov Chain Monte Carlo parameter estimation of
the white light curve, fitting for a transit model with
quadratic limb-darkening generated by pylightcurve
(Tsiaras et al. 2016) multiplied by a systematic trend
consisting of an exponential term and a linear term (as
in section 2.1). In the white light curve, we fit for Rp/R∗,
mid-transit time, a/R∗, i, quadratic limb-darkening coefficients and four parameters for the trend. Uniform
priors are used except for a/R∗ and i, where we apply
Gaussian priors based on values in Madhusudhan et al.
(2023b) and use the Kipping parameterisation (Kipping
2013) for limb-darkening priors. We fix the period to
32.940045 days (Benneke et al. 2019a), the argument of
periastron to 90o and the eccentricity to 0. The white
light curve parameter estimates are given in Table 1."
There are seven other paragraphs describing machinations and manipulations as bizarre and complex as these. It seems that at no point in these eight paragraphs do the authors give any justification for the weird convoluted spaghetti-code manipulations and transmogrifications that are occurring. There is nothing natural or straightforward about anything that is occurring. Something comparable would be occurring if you took a photo of a pine tree, and passed it through many different arbitrarily selected photo filters, to finally end up with a photo looking like a sexy woman, without ever justifying your use of any of those filters.

Finally the authors create some "model" that is basically a collection of guesses about 20 chemicals that might be in the atmosphere of this planet K2-18 b. Of course, their "model" includes their cherished gas dimethyl sulfide, because trying to gin up some evidence for that is the point of all these weird labors. Near the end of the paper, the authors triumphally announce that their model fits their pipeline-adjusted data.
This is pretty much just a big pile of baloney. No actual detection of dimethyl sulfide has occurred. The analysis pipeline is "keep torturing the data until it confesses" nonsense. There is no basis for any confidence in an analysis pipeline so convoluted and artificial. We can conclude with 99% confidence that the described analysis pathway is untrustworthy.
- Nothing reliable has been done in this paper to show any likelihood of the existence of dimethyl sulfide on this planet K2-18 b.
- Nothing reliable has been done in this paper to show any likelihood of the existence of any biomarker on this planet K2-18 b.
- No observations have ever been done to show a likelihood that water exists on this planet K2-18 b.
- In all likelihood (as suggested by the paper of Wogan) the planet K2-18 b is a gas planet like Neptune, with neither an ocean nor a land surface, a type of planet that should be incapable of supporting life. Not just Wogan's paper but also this 2025 paper make this conclusion, with the paper stating, "Our results, therefore, render the mini-Neptune scenario the most likely interpretation for K2-18 b, given current observational constraints."
Imagine if you have took the six hours of data that Madhusudhan played with to get his results, and gave such data to ten different teams of astronomers, asking them to tell you what the data suggested, without telling where in space the data came from. Not even one of such teams would tell you that a biomarker had been found, and not one of them would say that any evidence of dimethyl sulfide had been found. Madhusudhan's funny business here merely shows that when scientists have their hearts set on reporting the existence of some thing they are eagerly hoping to find, and when they are willing to exert unlimited weird labors playing around with their data, then they may report finding some trace of what they were so fervently desiring to find.
This is similar to what is going on in the world of neuroscience so frequently. Neuroscientists keep analyzing the noisy wavy blips of EEG readings, and they often report finding some faint sign of what they were eagerly hoping to find, after they subjected the data to many a strange convolution and contortion, in some arbitrary way, in a "keep torturing the data until it confesses" fashion. You can read about some examples of such a thing in my series of posts here.
Postscript: An Ars Technica article published after this post is entitled "Skepticism greets claims of a possible biosignature on a distant world." We read this:
"The last issue is whether, if dimethyl sulfide is really present on K2-18b, it was produced by life as it is here on Earth. The answer appears to be 'possibly not': A 2024 paper indicates it's possible to produce the chemical through light-activated reactions."
A CNN article has a false clickbait headline, and a bad scientist misstatement. But it least it has a good quote by astrophysicist Sara Seager, who states this:
"Now, with thousands of exoplanets in view, the temptation to overinterpret is strong — and some are jumping the gun. When it comes to K2-18 b, enthusiasm is outpacing evidence.”
The article also quotes a scientist named Schwieterman giving a technical reason for doubting that dimethyl sulfide was discovered at K2-18 b.
To get an analogy what it is like for astronomers getting spectroscopic data from a distant planet, consider the visual below:
This text consists of many different sentences, overlaid on top of each other. Imagine trying to extract a particular word from such a mess. That's pretty much impossible. It's a similar deal for an astronomer getting spectroscopic data from another planet, because what such a person gets is signals from many different elements and compounds and chemicals, arriving all at once. Unless you are very lucky, there is almost no way to reliably extract which part is a signal from which chemical, compound or element. But with a mess like an astronomer gets in such a situation (or a mess like the one shown above), there are unlimited opportunities to see what you are fervently hoping to see. All that can be truthfully said about such a mess is something like this: "The data is too noisy for me to say much of anything reliable about it."
I'm surprised to see some "question the hype" science journalism today in The Atlantic, where it's more typical to find credulous cheerleading of scientist boasts. Referring to Madhusudhan's team, an article there states this:
"The chemical [dimethyl sulfide] is one of several that could be responsible for the signal they found. And while it's the most likely one according to their models, others disagree."
The article notes that dimethyl sulfide was found "in the dead, icy spray of a comet," meaning it isn't any reliable biomarker. "Abiotic" refers to something not involving life. One paper is entitled "On the abiotic origin of dimethyl sulfide: discovery of DMS in the Interstellar Medium." Another paper is entitled "Evidence for Abiotic Dimethyl Sulfide in Cometary Matter."
In the Atlantic article we read a quote by astronomer Ignas Snellen stating that Madhusudhan's framing of his research is "irresponsible nonsense."
Madhusudhan's overenthusiasm reminds me of the overenthusiasm of another astronomer, Avi Loeb. Harvard astronomer Avi Loeb somehow got the idea that a 2014 meteor (the CNEOS 2014-01-08 meteor) may have been an interstellar spacecraft that blew up high in the sky. Loeb ran a million-dollar oceanic expedition looking for what he hoped would be remnants of a crashed extraterrestrial spaceship, an expedition he organized. He found no sign of anything looking like a spaceship or any of its parts. Loeb claims to have found tiny round specks only about a millimeter in size. All that he recovered were some tiny metal specks. The metal specks he found are just like metal sea specks found all over the world. But Loeb tried to suggest that he may have discovered smithereens of an exploded interstellar spacecraft.
There was nothing special about the specks Loeb and his team gathered (as I discuss here), and there is nothing special about the data Madhusudhan got from K2-18 b. Madhusudhan's readings are just like the readings from quite a few extrasolar planets that must be lifeless because they are outside of the habitable zone of the stars they revolve around. Loeb got a nice book deal out of his glory-hounding efforts, and one can wonder whether Madhusudhan's similar efforts may eventually pay off financially for him.
A National Geographic page interviews some experts about Madhusudhan's recent claims. Some excerpts:
'There's no reason to understand [DMS] as a unique consequence of life,' says Mathis. 'I just, for the life of me, cannot figure out exactly what the argument is about: why they think this could even potentially be indicative of life, given that we've seen abiotic sources.' ”
Post-postscript: An article at Gizmodo.com quotes some experts discussing Madhusudhan's recent paper: Planetary chemist Oliver Shorttle says "I do not believe the report of DMS in the spectrum of K2-18 b moves the astrobiological needle." He states this:
"There is presently no requirement from the data that this planet hosts liquid water oceans and a climate amenable to life. In fact, based on the data there is every reason to believe the climate will be far too hot for liquid water oceans, with the deep atmosphere potentially being underlain by oceans of magma, not liquid water. For this reason, even if 1 and 2 return a DMS detection, our expectation should be that this [molecule] has emerged in a lifeless, hot, sulfur and hydrogen rich atmosphere and ask ourselves what the atmospheric chemistry is that would have enabled this. Believing instead that this is DMS of biological origin would require overturning our every expectation as to the climate of this planet, without any other reason to do this from the data."
Astrophysicist Ignas Snellen says this:
"The whole thing is completely blown out of proportions.... The research team finds bumps in their spectrum. It is not clear whether these are real, and if so, what they could be caused by. There could be dozens of molecules (if real), or even cloud features. What do the authors do? They just look whether DMS [dimethyl sulfide] could cause this (and add DMDS). They ignore the dozens of other species [i.e. non-biological sources of molecules] that could cause this bump and call it a day. If I had been the referee, I would have stopped this publication right there. There is no reason to invoke astrobiology, let alone call it the biggest breakthrough or whatever....In the long run this will hurt astronomy when nobody will take us seriously anymore."
An NPR story says that a scientist has analyzed the most recent data from K2-18 b, and has found it has no signal of any kind. We read this: "The results he got suggested that there's too much noise in the data to draw any conclusions. Rather than seeing a bump or a wiggle that indicated a signal, 'the data is consistent with a flat line,' says Taylor, adding that more observations from the telescope are needed to know what can be reliably said about this planet's atmosphere."